Peter J McGuire Selected Research

Mechanistic Target of Rapamycin Complex 1

10/2021

PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.

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Peter J McGuire Research Topics

Disease

7	Infections 03/2022 - 12/2013
3	Inborn Urea Cycle Disorders 11/2019 - 02/2014
3	Human Influenza (Influenza) 01/2018 - 02/2014
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 06/2017
2	Virus Diseases (Viral Diseases) 10/2021 - 01/2019
2	Methylmalonic acidemia 05/2016 - 02/2010
2	Inborn Errors Metabolism (Inborn Errors of Metabolism) 05/2016 - 01/2016
2	Ornithine Carbamoyltransferase Deficiency Disease 01/2015 - 02/2014
2	Hyperammonemia 02/2014 - 12/2013
1	COVID-19 03/2022
1	Leigh Disease (Leigh's Disease) 01/2022
1	Chronic Granulomatous Disease 01/2022
1	Viremia 10/2021
1	Lymphadenopathy 10/2021
1	Rhabdomyolysis 01/2018
1	Liver Diseases (Liver Disease) 01/2018
1	Hypoglycemia (Reactive Hypoglycemia) 01/2018
1	VLCAD deficiency 01/2018
1	Cardiomyopathies (Cardiomyopathy) 01/2018
1	Sepsis (Septicemia) 01/2016
1	Glutaric Acidemia I 04/2014
1	Homocystinuria 02/2010
1	Late Onset Disorders 02/2010
1	Methylmalonic acidemia with homocystinuria 02/2010
1	Propionic Acidemia 02/2010

Drug/Important Bio-Agent (IBA)

4	EnzymesIBA 11/2019 - 02/2014
3	Amino Acids FDA Link 01/2016 - 02/2014
2	CytokinesIBA 01/2022 - 02/2014
2	Urea (Carbamide)FDA LinkGeneric 11/2019 - 02/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2018 - 11/2015
2	NitrogenIBA 01/2016 - 11/2015
1	Immunoglobulin M (IgM)IBA 03/2022
1	AntibodiesIBA 03/2022
1	RotenoneIBA 01/2022
1	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2022
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 10/2021
1	Mechanistic Target of Rapamycin Complex 1IBA 10/2021
1	ChromatinIBA 10/2021
1	Poly I-CIBA 01/2019
1	acylcarnitineIBA 01/2018
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 06/2017
1	Methylmalonyl-CoA MutaseIBA 05/2016
1	Neutralizing AntibodiesIBA 05/2016
1	LipidsIBA 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	glutaric acidIBA 04/2014
1	glutaryl-coenzyme A (glutaryl-CoA)IBA 04/2014
1	Ornithine Carbamoyltransferase (Ornithine Transcarbamylase)IBA 02/2014
1	OrnithineIBA 02/2014
1	Arginine (L-Arginine)FDA Link 02/2014
1	Transaminases (Aminotransferases)IBA 02/2014
1	Aspartic Acid (Aspartate)FDA Link 02/2014
1	AmmoniaIBA 12/2013
1	Methionine (L-Methionine)FDA Link 02/2010
1	Hydroxocobalamin FDA Link 02/2010
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 02/2010
1	propionylcarnitineIBA 02/2010

Therapy/Procedure

1	Critical Care (Surgical Intensive Care) 01/2016
1	Nutritional Support (Artificial Feeding) 01/2016
1	Length of Stay 12/2013